The Mevalonate Pathway and HMG-CoA Reductase Inhibition

To understand the risks associated with statins, it’s important to first look at the biochemical processes they interfere with. Statins work by inhibiting the enzyme HMG-CoA reductase, which plays a central role in the mevalonate pathway. This pathway is responsible for producing cholesterol as well as several other vital molecules that are essential for overall health.

While statins block the production of cholesterol, they also disrupt the synthesis of other critical compounds in the body. By inhibiting HMG-CoA reductase, statins limit the production of coenzyme Q10 (CoQ10), a powerful antioxidant that plays a crucial role in cellular energy production. CoQ10 is involved in the electron transport chain within mitochondria, where energy is produced. Without sufficient CoQ10, cellular energy production becomes impaired, which can lead to muscle weakness, fatigue, and even muscle death (myopathy). This is why muscle pain and discomfort are common complaints among statin users.

The Impact on Muscle Health

Muscle-related side effects are one of the most frequently reported issues among statin users. CoQ10 depletion is a major factor contributing to these problems. Without CoQ10, muscles lack the energy required to function properly, leading to discomfort, weakness, and in severe cases, muscle tissue damage. This condition, known as statin-induced myopathy, can severely impact the quality of life, causing chronic pain and limiting physical activity.

Statins and Diabetes: A Hidden Risk

In addition to affecting muscle health, statins also have an impact on insulin sensitivity. The mevalonate pathway is responsible for synthesizing dolichol, a molecule that plays a role in maintaining proper insulin function. When statins reduce the production of dolichol, it can negatively affect the body’s ability to regulate blood sugar, increasing the risk of developing type 2 diabetes. This risk is especially concerning for individuals who may already be predisposed to metabolic issues.

Statins and Vitamin K2 Deficiency

Another overlooked side effect of statins is their impact on vitamin K metabolism. Statins reduce the production of geranylgeranyl pyrophosphate, a molecule that is essential for converting vitamin K1 into its active form, vitamin K2. Vitamin K2 is important for calcium regulation in the body, ensuring that calcium is directed to the bones and not deposited in the arteries. A deficiency in vitamin K2 can contribute to arterial calcification and increase the risk of heart attacks—an effect that contradicts the very reason why statins are prescribed in the first place.

Hormonal Imbalances: Testosterone and Estrogen

Statins can also affect hormone levels, leading to sexual and reproductive health issues. In men, statins have been shown to reduce testosterone production, which can lead to erectile dysfunction, reduced libido, and other symptoms associated with low testosterone. Women aren’t immune to the hormonal effects of statins either, as these drugs can reduce estrogen levels, potentially leading to menstrual irregularities, lower libido, and other symptoms of hormonal imbalance. These side effects are often downplayed or dismissed by pharmaceutical companies, but they can have a significant impact on a person’s overall well-being.

The Pharmaceutical Industry and Statin Side Effects

Pharmaceutical companies have long marketed statins as a miracle drug for heart disease, emphasizing their ability to lower cholesterol and reduce the risk of heart attacks. However, the side effects of statins are often minimized or brushed off as "rare" or "mild" issues that are merely "side effects." In reality, many of these side effects are not just incidental—they are the direct consequences of the drugs' mechanism of action.

While statins may be necessary for certain individuals at high risk for cardiovascular disease, the risks and benefits should always be carefully weighed. For some people, the side effects of statins may outweigh their potential benefits, and alternative methods of managing cholesterol and heart health should be explored.

Conclusion

Statins are powerful drugs that have saved many lives, but they are not without risks. By blocking the mevalonate pathway and inhibiting the production of crucial molecules like CoQ10, dolichol, and geranylgeranyl pyrophosphate, statins can cause a range of serious side effects. These include muscle pain, fatigue, diabetes, heart disease, hormonal imbalances, and even cognitive decline. It’s important for anyone considering statins to be aware of these potential risks and to have a thorough discussion with their healthcare provider about the best approach to managing their heart health.

As always, it’s crucial to stay informed and advocate for your own health. While statins may be appropriate for some, they are not a one-size-fits-all solution. Exploring lifestyle changes, dietary modifications, and other natural therapies could provide a safer and more effective path to long-term health. system.

How to reverse type 2 diabetes, lose weight, prevent chronic infection such as high blood pressure, heart attack including cancer presentation---START TODAY!

Reversing type 2 diabetes, losing weight, and preventing chronic conditions like high blood pressure, heart disease, and cancer can be achieved naturally by adopting a holistic lifestyle focused on cellular health. By avoiding processed foods and limiting carbohydrate intake to a defined amount, while completely eliminating seed oils, you can improve insulin sensitivity and promote healthy cell membrane function. Proper electrolyte balance is essential to prevent the initial cell membrane depolarization, which triggers harmful ion imbalances responsible for chronic diseases. Focus on stress reduction, proper hydration, and quality sleep to enhance your body’s ability to prevent oxidative stress, inflammation, and free radical damage. By embracing these natural approaches, you can significantly reduce your risk of chronic conditions and support overall wellness.

Are you tired of battling type 2 diabetes, struggling with weight loss, or worried about the risks of chronic diseases like high blood pressure, heart attack, and even cancer? It's time to take control of your health with proven, science-backed strategies that can help you not only reverse type 2 diabetes, but also shed excess weight and protect yourself from life-threatening conditions.

Imagine living a life free from daily medication, feeling energized, and knowing you're preventing dangerous diseases that impact millions worldwide. Thousands of individuals have already transformed their lives with our step-by-step guide, and now it's your turn. This isn’t just another fad diet or quick fix—it’s a holistic approach to long-term health and wellness.

What you’ll discover:

• The truth about reversing type 2 diabetes naturally

• Simple, effective strategies for losing weight without starving yourself

• Key dietary changes that help prevent chronic diseases like heart attack, high blood pressure, and even cancer

• Tips to boost your energy levels and improve your overall well-being

You deserve a healthy life, free from the worries of chronic illnesses. Take the first step today and join thousands of others who’ve already seen results!

This presentation is for you if

§Diabetic or prediabetic

§High blood pressure

§Any Insulin Resistance Complications

§CVD

§Alzheimer’s

§Cancer

§For young healthy individual who cares to preserve a good quality of life 10, 20, 30 years from now

2. Disclaimer

•Glenn Rosaroso Vale is not a doctor, but I have worked in the medical field for over 35 years in the laboratory. The information shared in this webinar is for informational purposes only and should not be taken as professional medical advice or recommendations. Please consult your healthcare provider before making any changes to your lifestyle or medical regimen based on this information."

•"The presenter and RootCausePrevention.com take no responsibility for any actions you may take based on the content presented in this webinar or the website. The information provided is meant to educate and inspire, not to diagnose, treat, or cure any medical conditions. Please always seek the advice of your physician or healthcare provider before acting on any information presented here."

Empower Yourself to Lead The Right Path To Reversal

3. Meet The presenter

Welcome You All in This Presentation

·My name is Glenn Rosaroso Vale, BSMT( MS(IT), MBA

·I have been in the medical field for more than 35 years

·Personal health challenges passionately motivate me to share with the world

·The importance of reversing Type 2 diabetes and preventing chronic diseases like high blood pressure, heart attacks, and cancer is crucial for having a good quality of life in the future.

4. What is Type 2 Diabetes? A Progressive Disease

• That can end up in an ESRD

• Many Chronic Complications

• It progresses with the traditional medication and it worsens over time without prorper intervention.

• This can be reverse through natural way

• Diabetes starts with cell membrane depolarization

• Preventing cell depolarization is our first defense through natural way

• Then tightly regulate the ions causing to trigger different enzymatic reactions that activate different down stream pathological pathways

• For example: An enzyme thromboxane synthase is upregulated in elevation of this ions producing a clot in myocardial infarction. Other enzymes are also upregulated in an elevation of these ions producing prostaglandin (PGH2), leukotienes, and other inflammatory cytokines molecules from omega 6 consumption

• We must tightly regulate these ions in a natural way

• If these ions are not regulated, it can cause ion overload, leading to mitochondrial dysfunction, which results in fatigue and weakness. This can eventually contribute to high blood pressure, heart attack, diabetes, and even cancer.

• Do not wait, act now before it's too late and stop the progression of the disease

LIPID BILAYER

CELL MEMBRANE

MITOCHONDRIA

5. Traditional Medications: Building a Cycle of Progression

• The cycle that medications create: symptom management but not disease reversal. For example, treating the sugar, treating insulin, and treating insulin resistance. All of this addresses the symptoms, not the root cause.

• These are all like a temporary band-aid or patches on your wound

• The long-term effects and dependency on these medications are chronic diseases such as high blood pressure, worsening type 2 diabetes, heart attack, Alzheimer’s, and even cancer.

• Diabetes will never reverse, it will worsen

• By empowering you with the knowledge, you cab decide the right path to reversal

6. The Yo-Yo Effect of Traditional Approaches

• Conventional weight loss methods and diets lead to temporary results, followed by inevitable weight regain.

• This creates a cycle of frustration and failure.

7. Why Current Diets Won’t Work

• Popular diets (e.g., low-fat, low-carb, fad diets) don't address the root cause of Type 2 diabetes and chronic diseases.

• These diets lead to temporary fixes but don't offer sustainable results.

• It does not fix the polyol pathway. This is the pathway that starts the disease progression. Managing this pathway will solve the problem

8. The Root Cause: Why We Need a New Approach

• The core issues that drive Type 2 diabetes and chronic diseases (Not Sugar, Not insulin resistance, not inflammation not , nutrient deficiencies, etc.).

• Simply addressing symptoms isn’t enough for long-term health

• We must address the real root cause of the disease. What initiated the downward pathological reactions is our main target to stop the progression

• Regulation of these simple positively charged ions which is the root cause that triggers a series of enzymatic reactions that lead to destructions of the cells

• Regulation of these ions is the holy grail of almost all the disease progression processes

• .All factors that cause to increase these particular ions must be avoided

9. Breaking the Cycle: A Holistic, Sustainable Approach

• Presenting a more effective solution that addresses the root causes rather than just masking symptoms.

• Our Strategy are tightly regulating these simple ions as the real root cause of all

• First, we try to avoid the initial cell membrane depolarization of the lipid bilayer causing an increase of these ions responsible for the next succeeding pathological reactions

• Second, we regulate these ions tightly avoiding wide fluctuations

• Third, we try to prevent gene mutation caused by elevation of these ions

• We can stop the progression of the diseases

• Do not expect a result if you do not follow our strategy. It takes disciplined The importance of nutrition, lifestyle changes, and mindset in reversing Type 2 diabetes and preventing chronic diseases are crucial for the success.

10. Why Your Current Strategy Isn’t Enough

• The drawbacks of the traditional approaches and why they fail to provide lasting result are they are addressing the symptoms not the root cause of the disease

• Without addressing the underlying causes, Type 2 diabetes will continue to worsen

11. How This Approach Helps You Lose Weight & Prevent Chronic Diseases

·The new method will help with weight loss, lowering blood pressure, reducing the risk of heart disease, and preventing cancer through natural way by changing lifestyle

Marites albano

• I am a cancer patient stage ½ . It’s now metastasize in my lungs. I want to live longer

• I glad I was able to talk to Glenn Vale for my diet plan

• In conjunction with my treatment and diet plan. I think I have the chance to survive, I feel good so far and I will continue my diet plan

• Thank you Glenn Vale

testimony

Aimee P. Panisal

• I used to be big. I decided to follow Glenn’s diet plan and the book The Twin Devils That Sabotage Our Health, which teaches me what to eat and what not to eat. I lost 60 lbs and feel great. I do not have any chronic diseases, and I thank God for that.

testimony

RhenRen Yap

• I used to be big-built, and I would eat whatever I wanted and feel great, until I developed obstructive jaundice. Now, I have decided to follow the advice in Glenn Vale's book The Twin Devils That Sabotage Our Health, and it has made a big difference.

testimony

ShIEla May martinez

• I am young and feel healthy, but I am surrounded by family members with diabetes. My sister has PCOS. I want to prevent all those chronic diseases because they run in the family. I decided to follow Glenn Vale’s book The Twin Devils That Sabotage Our Health. I still feel great and am trying to maintain my weight.

testimony

12. Introducing My Book: The Twin Devils That Sabotage Our Health

• The book, emphasizing how it outlines the step-by-step approach to health and wellness.

• It’s a comprehensive guide for those serious about making lasting health changes.

• This book will guide you how to reverse your diabetes through natural way

• This can help you regulate and reveal that ions causing the trigger of initial pathologic downstream reactions

• Act now, Do not wait. The disease is progressive

  Maybe I am like you before, I said I feel fine but deep inside my body is slowly dying and it was too late I end-up ESRD. I don't want to happen to all of you. That is why I am sharing my experience

13. Get the E-Book Today & Take Action

Buy now—diabetes is a progressive condition. You might feel fine today, but over time, symptoms can worsen, and by then, it could be too late. Don't wait until it's too late—take action now to avoid potentially severe consequences, like the need for dialysis.

Thank
you FOR WATCHING THE presentation AND CLICK THE LINK TO PURCHASE THE BOOK

• Glenn Rosaroso Vale, BSMT, MS(IT), MBA

  903-268-6664

  info@rootcauseprevention.com

  grfv@sbcglobal.net

  www.rootcauseprevention.com